LAMP-CRISPR MICROFLUIDICS ON PAPER: NEW DEVICES FOR BIOMEDICAL DIAGNOSTICS

Are you interested in rapid, sensitive, and accurate diagnostics with the potential to meet point-of-care (POC) testing requirements? The R&D team at DNAiTECH is thrilled to share the preprint of their work on developing a paper-based microfluidic platform for detecting nucleic acids with high sensitivity and specificity. Here we use LAMP coupled with CRISPR/Cas12a fluorescent detection technology to accurately signal the presence of LAMP amplified product on a microfluidic paper chip. Check out the link here:

https://www.biorxiv.org/content/10.1101/2023.03.02.530841v1

LAMP is powerful. LAMP combined with CRISPR is even more so. It is robust, fast and visually intense. Positive reactions can be seen by the naked eye or captured by a smartphone. We are the first to bring LAMP and CRISPR together on a low-cost paper-based microfluidics chip. This development, and the release of S-TECH, our sample extraction technology, are two significant milestones on our road to developing equitable point-of-care diagnostics.