LAMP-CRISPR MICROFLUIDICS ON PAPER: NEW DEVICES FOR BIOMEDICAL DIAGNOSTICS

Interested in diagnostics that are rapid, sensitive, and accurate with potential to meet point-of-care (POC) testing requirements? The R&D team at DNAiTECH is thrilled to share the

preprint of their work on developing a paper based microfluidic platform for detecting

nucleic acids with high sensitivity and specificity. Here we use LAMP coupled with

CRISPR/Cas12a fluorescent detection technology to accurately signal presence of LAMP

amplified product on a microfluidic paper chip. Check out the link here.

https://www.biorxiv.org/content/10.1101/2023.03.02.530841v1

LAMP is powerful, LAMP combined with CRISPR is even more so, it is robust, fast and visually intense. Positive reactions can be seen by the naked eye or captured by smartphone. We are the first to bring LAMP and CRISPR together on a low cost paper based microfluidics chip. This development, and the release of S-TECH, our sample extraction technology, are two significant milestones on our road to the development of equitable point-of-care diagnostics.