Portable nucleic acid amplification technology for point-of-care diagnostics
Mauri ora te whenua, mauri ora te tāngata.
The Cawthron Marlborough Environments Award night was held on April 20th 2023, and we were thrilled to have won the Business Innovation award and to be the Supreme winners. This was quite unbelievable for us and a boost for the DNAiTECH team. Thank you to all the fantastic people who have supported us on our DNAiTECH journey; it is only beginning.
DNAiTECH : Technology for point-of-care diagnostics.
DNAiTECH Ltd is a New Zealand-based biotechnology company developing innovative point-of-care (POC) diagnostics systems.
We aim to meet the challenge of POC testing, fulfilling the World Health Organisation’s ASSURED criteria and delivering rapid, robust molecular tests for use beyond the laboratory.
Our ongoing R&D application areas encompass pathogen detection for biomedical, environmental and Agritech applications.
We use the powerful isothermal amplification method LAMP (loop-mediated amplification) for all our applications for pathogen detection. We are first to fully integrate LAMP-CRISPR in a low cost paper based microfluidic system. See below for more information on PLACID, our Gen3 diagnostic system.
Our current available technologies are S-TECH and the DNAiTECH generation 2 isothermal instrument.
S-TECH is our front-end sample processing technology. This system enables the isolation of nucleic acids from any type of sample. S-TECH has been used for a large range of sample extractions, including nasal swabs, throat swabs, urine, faeces, soil, and plant tissue. Using S-TECH highly purified DNA can be prepared that is inhibitor-free for isothermal molecular amplification.
Second Generation DNAiTECH Instrument
Our generation 2 DNAiTECH instrument is a
tube-based, battery-powered, portable system for isothermal amplification that is field deployable. The device combines Android smartphone technology with a simple Bluetooth connected handheld-instrument that uses isothermal DNA amplification chemistry. The temperature range of this instrument is from 37-70C, enabling the use of a range of isothermal methods, including loop-mediated isothermal amplification (LAMP), rolling circle amplification (RPA), recombinase polymerase amplification (RCA), and helicase-dependent amplification (HDA).
Third Generation DNAiTECH Instrument
We have pioneered the integration of LAMP with CRISPR on a simple paper-based microfluidic system. This technology is being incorporated into the Gen-3 technology platform that will include multiple target testing and multi-sample testing on simple, low-cost portable microfluidic paper-based systems. The generation 3 platform is planned for release in 2024.